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Spurs vs. Timberwolves Odds, Prediction, Time: 2026 NBA Playoff Picks and Game 1 Best Bets

Posted on May 5, 2026

The sixth-seeded Minnesota Timberwolves take on the second-seeded San Antonio Spurs in Game 1 of their Western Conference semifinal series on Monday night as the 2026 NBA playoffs continue. Minnesota advanced with a solid 110-98 victory over the Denver Nuggets, while San Antonio rolled past Portland 114-95. The Wolves finished 49-33 overall and showed strong road form at 24-20 away from home, including postseason play. The Spurs dominated the Southwest Division at 62-20, boasting an impressive 34-9 record at home.

Tipoff is scheduled for 9:30 p.m. ET at Frost Bank Center in San Antonio. The Spurs are listed as 9.5-point favorites in the latest betting odds, with the over/under set at 219.5 total points. Anthony Edwards (knee) is questionable for Minnesota, and Ayo Dosunmu (calf) has been ruled out.

The SportsLine Projection Model has simulated this matchup 10,000 times and is sharing its top Timberwolves vs. Spurs picks. The model has delivered strong results this season, going 25-9 (74%) on its top-rated NBA spread selections.

Current Game Odds Spread: Spurs -6.5 Total: Over 201.5 / Under 201.5 Moneyline: Spurs -250 / Timberwolves +265 (updated lines may vary by sportsbook)

The model is leaning Over on the total. The Over has landed in five of the last seven head-to-head meetings between these teams and in five of Minnesota’s last nine games. San Antonio ranked third in the league for scoring during the regular season at 119.8 points per game, while the Timberwolves averaged 118 points.

Projections show Minnesota with five players reaching double figures, led by Julius Randle at 21.9 points. Victor Wembanyama is expected to pace the Spurs with 25.3 points, supported by six teammates in double figures. The model projects a combined total of 222 points, with the Over hitting in 54% of simulations.

For the full Timberwolves vs. Spurs spread pick and best bets, head to SportsLine. Stream the game live on Fubo.

This matchup features two high-powered offenses meeting in a hostile environment for Minnesota, setting up an exciting start to the series with plenty of scoring potential.

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